PCOS polycystic ovary syndrome

What is PCOS?

Polycystic ovary syndrome (PCOS) refers to the condition of hormonal imbalance that is often present among females of reproductive age. Analysts suggest that PCOS affects 8–13% of women in the general population, and about half of them go undiagnosed. Among the complications of PCOS include irregular menstrual periods, abnormal levels of androgen (male hormones), infertility and ovarian cysts among others. Such symptoms do not only affect physical health but also emotional health. Quality of health is also affected in women with PCOS. Macie Medical helps in raising awareness and disseminating information regarding PCOS and its effects on women’s health alongside useful resources, advice, and examples women suffering from the condition can use to tackle the problem and enjoy decent health and quality of life. 

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Causes and Risk Factors

Researchers have not clearly identified the precise mechanism behind the development of PCOS. However, they believe that multiple factors—such as family history, physical activity levels, and overall health—can disrupt the female hormonal system. These disruptions often lead to elevated male hormone (androgen) levels, irregular menstrual cycles, and various other physical symptoms.Some of the possible factors that may contribute to PCOS are: 

  • Insulin resistance: This is how insulin works – it assists the body’s cells to utilize glucose, which is the energy source in the body. When cells fail to utilize glucose properly despite the presence of insulin, blood sugar levels rise. In response, the body increases insulin secretion to lower the glucose levels. Excess insulin then stimulates the ovaries to produce large amounts of male hormones, known as androgens, such as testosterone. Excess testosterone contributes to interruptions in normal ovulation and aids in abrupt skin eruptions along with excessive hair growth. 
  • Genetic factors: Because PCOS runs in families, scientists assume that certain alleles play a role. They are actively researching the genes that may contribute to the development of PCOS.
  • Inflammation: The immune system initiates inflammation as a physiological response to eliminate infection or injury. However, prolonged inflammation primarily causes suffering and often leads to various illnesses. Patients with PCOS often show increased levels of inflammatory markers in their blood, which may contribute to insulin resistance and excessive production of androgens.

Other Risk Factors Include:

  • Obesity: Excess body weight appears to enhance insulin resistance and inflammation which can be a risk factor for other complications. 
  • Family history: If the mother, sister, or aunt has PCOS, it is more likely that it will apply to the affected person. 
  • Type 2 diabetes: Women suffering from PCOS have higher chances of contracting type 2 diabetes, especially those with diabetes in their family or who are obese. 

Complications and Consequences

PCOS is not only a reproductive disorder as PCOS is also a metabolic disease and psychological one. With Polycystic Ovary Syndrome, women tend to incur greater complications like cardiovascular disorders, endometrial cancer, mental disorders, and social stigma. 

Some of the statistics and examples of these issues are: 

  • Cardiovascular disease: There is a greater chance of having heart attack and stroke among women with PCOS owing to conditions such as Hypertension, high cholesterol positivity and inflammation which increases absorption of fat in PDV. 
  • Endometrial cancer: The absence or irregular menses in women with PCOS more often than not results in hyper-thickening of the endometrial lining of the womb which comes with a price in terms of including cancer of the endometrial lining particularly when not treated. 
  • Mental health problems: Infertility and the physical symptoms of the condition together with social implications may cause psychological issues among these women. Depression, anxiety, low self-confidence, negative body image as well as positive body image and eating disorders may be encountered. 
  • Social stigma: People discriminate against them and treat them with negative social attitudes due to their body shapes, infertility, and other health-related issues. The lack and incomprehensive understanding of PCOS may hinder them in forms of personal, occupational and social. 
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Diagnosis and Treatment

Women of reproductive age may develop PCOS which is an endocrine disorder which several complications are associated with. These include such issues as amenorrhea, hirsutism, anovulatory infertility and polycystic ovaries. The Rotterdam criteria require that at least 2 of the following are present to make a diagnosis of PCOS in practice polycystic. 

  • Signs or symptoms of high androgens, such as acne, hirsutism (excessive hair growth), or alopecia (hair loss). 
  • Irregular periods, meaning fewer than eight menstrual cycles per year or cycles longer than 35 days (about 1 month, 4 and a half days). 
  • Polycystic ovaries, meaning ovaries that have 12 or more follicles (small fluid-filled sacs) or an increased volume, as seen on an ultrasound 

Other possible causes of these features, such as thyroid disorders, adrenal disorders, or tumors, must be ruled out before making the diagnosis of PCOS. 

The treatment of PCOS depends on the individual goals and concerns of each woman. 

Some of the common treatment options are:

  • Lifestyle changes, such as losing weight, eating a healthy diet, and exercising regularly, can improve insulin sensitivity, lower androgen levels, regulate periods, and reduce the risk of diabetes and heart disease. 
  • Medications, such as birth control pills, anti-androgens, metformin, or clomiphene, can help with different aspects of PCOS, such as hormonal balance, acne, hirsutism, ovulation, and fertility. Some newer medications, such as letrozole, may also be effective for inducing ovulation and increasing pregnancy rates. 
  • Fertility treatments, such as intrauterine insemination (IUI) or in vitro fertilization (IVF), can help women with PCOS who have difficulty conceiving naturally. These treatments may require the use of medications to stimulate the ovaries and monitor the development of the eggs. 

Early diagnosis and treatment of PCOS are important to prevent long-term complications, such as endometrial cancer, diabetes, cardiovascular disease, and mental health problems. Treatment can also improve the quality of life and wellbeing of women with PCOS by addressing their physical and emotional symptoms. 

Conclusion

In conclusion, PCOS is a common hormonal condition that affects women of reproductive age. It can cause various symptoms, such as irregular periods, excess androgen, infertility, and polycystic ovaries. PCOS can also increase the risk of serious health problems, such as cardiovascular disease, endometrial cancer, mental health problems, and social stigma. This can be diagnosed by the presence of at least two of three criteria: signs or symptoms of high androgens, irregular periods, and polycystic ovaries. PCOS can be treated with lifestyle changes, medications, and fertility treatments, depending on the individual goals and concerns of each woman. Early diagnosis and treatment of PCOS are important to prevent long-term complications and improve quality of life. 

Tips and Resources

If you have PCOS, you are not alone. There are many resources and support groups that can help you cope with your condition and live a healthy and happy life. Some of the tips and resources for women with PCOS are: 

  • Eat a well-balanced diet that is rich in whole foods, anti-inflammatory foods, and plant-based protein sources. Avoid processed, sugary, and high-carb foods that can worsen insulin resistance and inflammation. 
  • Maintain a healthy weight and exercise regularly. This can help improve insulin sensitivity, lower androgen levels, regulate periods, and reduce the risk of diabetes and heart disease. 
  • Manage your stress and sleep well. Stress and sleep deprivation can affect your hormones and mood. Try to practice relaxation techniques, such as meditation, yoga, or breathing exercises, and get enough sleep every night. 
  • Avoid exposure to endocrine disruptors, such as pesticides, plastics, and cosmetics, that can interfere with your hormone balance. 
  • Consider alternative therapies, such as acupuncture, that may help with some aspects of PCOS, such as ovulation, menstrual cycles, and fertility. 
  • Join a support group, such as [PCOS Challenge] or [PCOS Awareness Association], that can provide you with emotional support, education, and advocacy. 
  • Seek professional help if you need it. Talk to your doctor, gynecologist, endocrinologist, nutritionist, psychologist, or other health care providers who can help you with your specific needs and goals. 

Finally

I hope this blog has been helpful and informative for you. PCOS is a challenging condition, but it can be managed with the right care and support. You are not defined by your PCOS. You are a strong, beautiful, and capable woman who can achieve anything you set your mind to. 

I invite you to share your stories and experiences with PCOS in the comments section below. Let’s create a supportive and empowering community of women with PCOS. And remember, if you have any questions or concerns, don’t hesitate to reach out to your health care provider or Macie Medical, we have a personalized care program that offers better support for women with PCOS. 

Thank you for reading and stay tuned for more updates on PCOS and women’s health. 

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Hello! I am Dr Judith Aniekwena
Board certified in internal medicine and obesity medicine specialist.
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